Free Download Emerging Roles for Hippocampal Adult Neural Stem Cells in Memory (Colloquium Series on Stem Cell Biology)

PDF Emerging Roles for Hippocampal Adult Neural Stem Cells in Memory (Colloquium Series on Stem Cell Biology)

PDF Emerging Roles for Hippocampal Adult Neural Stem Cells in Memory (Colloquium Series on Stem Cell Biology)

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Book Details :
Published on: 2013-12-12
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Original language: English

Approximately 50 years ago, newly generated neurons were discovered in the adult hippocampus of the rat brain. This discovery contradicted a key principle in mammalian developmental neurobiology—that all the neurons of the brain are made during early development—and led to intensive study to find out how new neurons are generated and how the process of neurogenesis is regulated. Since then, a unique population of adult neural stem cells has been identified, and many of the molecular pathways that control their self-renewal, proliferation, and cell fate have been elucidated. However, the presence of new neurons in the adult brain also poses intriguing functional questions that have, as yet, gone largely unanswered. Why is adult neurogenesis restricted to select brain regions What functional benefit do these new cells confer Indeed, the field of adult neurogenesis offers a unique opportunity to study naïve neurons as they mature, form connections with existing neural networks, and begin to participate in information processing. We review the basics of adult NSC biology and the maturation of newborn neurons. In particular, we focus on new neurons in the hippocampus, and how they contribute to function in this key memory-forming structure of the brain. Table of Contents: Acknowledgments / Introduction / A Day in the Life of a Hippocampal Neural Stem Cell / Dynamic Regulation of Neurogenesis and Maturation / The Function of New Neurons / Neurogenesis as a Regulator of Affective State / Conclusions / References / Author Biographies web.mit.edu / jik/src/Attic/kerberos_ password - . .mn 0 01 05_1 1 10 100 10th 11 11_d0003 12 13 14 141a 143b 15 16 17 17igp 18 19 1900 1901 1902 1903 1904 1905 1906 1907 1908 1909 1910 1911 1912 1913 1914 1915 ... Multiple Sclerosis NEJM Epidemiologic Features. The prevalence of multiple sclerosis varies considerably around the world. 13 Kurtzke classified regions of the world according to prevalence ... Full text of "NEW " - Internet Archive Search the history of over 279 billion web pages on the Internet. Le Live Marseille : aller dans les plus grandes soires ... Retrouvez toutes les discothque Marseille et se retrouver dans les plus grandes soires en discothque Marseille. Oral Fingolimod (FTY720) for Relapsing Multiple Sclerosis ... Original Article. Oral Fingolimod (FTY720) for Relapsing Multiple Sclerosis. Ludwig Kappos M.D. Jack Antel M.D. Giancarlo Comi M.D. Xavier Montalban M.D. Paul ... Oxbridge essays scampi shrimp recipe nobu-zzvc Oxbridge essays scampi shrimp recipe nobu-zzvc Samedi 14 mar 2015
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